Efficacy of Botulinum Toxin-A Injections in Masticatory Muscles for the Management of Bruxism: A Clinical Perspective

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Submitted: May 13, 2025
Published: May 21, 2025
DOI: 10.29328/journal.jcad.1001047

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Mehdi Khemiss
Faculty of Dental Medicine, University of Monastir, Tunisia
Zoubaier Baya
Department of Dental Medicine, Fattouma BOURGUIBA University Hospital, Monastir, Tunisia
Fathi Haddaoui
Research Laboratory LR12SP10: Functional and esthetic Rehabilitation of the maxillae, Farhat HACHED University Hospital, Sousse, Tunisia
Moncef Bey
Faculty of Dental Medicine, University of Monastir, Tunisia

Abstract

Bruxism, characterized by involuntary, repetitive jaw-muscle activity including clenching and grinding of teeth, can lead to significant dental and muscular complications. Conventional treatments—such as occlusal splints and behavioral therapy-may not fully address muscular hyperactivity. Botulinum toxin type A (BoNT-A), a neurotoxin that inhibits acetylcholine release at neuromuscular junctions, has emerged as a promising therapeutic option. This article reviews clinical studies regarding the efficacy of BoNT-A injections into masticatory muscles for bruxism management, with a focus on clinical outcomes, safety, and practical considerations.

Article Details

Khemiss, M., Baya, Z., Haddaoui, F., & Bey, M. (2025). Efficacy of Botulinum Toxin-A Injections in Masticatory Muscles for the Management of Bruxism: A Clinical Perspective. Journal of Clinical Advances in Dentistry, 001–002. https://doi.org/10.29328/journal.jcad.1001047
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