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Efficacy of Botulinum Toxin-A Injections in Masticatory Muscles for the Management of Bruxism: A Clinical Perspective

Published on: 21st May, 2025

Bruxism, characterized by involuntary, repetitive jaw-muscle activity including clenching and grinding of teeth, can lead to significant dental and muscular complications. Conventional treatments—such as occlusal splints and behavioral therapy-may not fully address muscular hyperactivity. Botulinum toxin type A (BoNT-A), a neurotoxin that inhibits acetylcholine release at neuromuscular junctions, has emerged as a promising therapeutic option. This article reviews clinical studies regarding the efficacy of BoNT-A injections into masticatory muscles for bruxism management, with a focus on clinical outcomes, safety, and practical considerations.
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